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LEXICARE®Sodium Picosulfate BPStimulant Laxative
LEXICARE® SYRUP
Stimulant LaxativeSodium Picosulfate
LEXICARE (sodium picosulphate BP) is a stimulant laxative oral solution containing 5 mg sodium picosulfate per 5 ml, used for short-term relief of constipation. It is a prodrug that is converted by colonic bacteria into an active metabolite, which acts locally in the colon to stimulate peristalsis and promote water and electrolyte accumulation in the bowel, helping soften stools and trigger bowel movement.
- Dosage form
- Syrup
- Strength
- 5 mg/5 ml
- Composition
- Each 5 ml oral solution contains Sodium picosulphate BP 5 mg.
- Pack sizes
- Lexicare Oral Solution: Each bottle contains 100 ml Oral Solution.
Manufactured by Doctor's Chemical Works Ltd.
Prescribing information
Pharmacology
Sodium picosulfate is a triarylmethane group derivative stimulant laxative. After oral administration it is activated by the colonic bacteria and acts locally in the colon. The active form then stimulates the nerve endings of the intestinal wall and results in colonic peristalsis with promotion of accumulation of water and electrolytes in the colonic lumen. This results in stimulation of defecation, reduction of transit time and softening of the stool. Stimulation of the rectum causes increased motility and a feeling of rectal fullness. The rectal effect may help to restore the “call to stool”.
